Gtf2ird1-flox 基因敲除小鼠

1. Nambara, Sho, Masuda, Takaaki, Kobayashi, Yuta, Sugimachi, Keishi, Mimori, Koshi. 2019. GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor-suppressor gene TGFβR2 in colorectal cancer. In Cancer science, 111, 343-355. doi:10.1111/cas.14248. https://pubmed.ncbi.nlm.nih.gov/31758608/

2. Palmer, Stephen J, Tay, Enoch S E, Santucci, Nicole, Gunnning, Peter W, Hardeman, Edna C. 2006. Expression of Gtf2ird1, the Williams syndrome-associated gene, during mouse development. In Gene expression patterns : GEP, 7, 396-404. doi:. https://pubmed.ncbi.nlm.nih.gov/17239664/

3. Huo, Yongliang, Su, Timothy, Cai, Qiuyin, Macara, Ian G. 2016. An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter. In Cell reports, 15, 2089-2096. doi:10.1016/j.celrep.2016.05.011. https://pubmed.ncbi.nlm.nih.gov/27239038/

4. Zhuang, Hongkai, Zhang, Chuanzhao, Hou, Baohua. . GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer. In Bioscience reports, 40, . doi:10.1042/BSR20202150. https://pubmed.ncbi.nlm.nih.gov/32936232/

5. Canales, Cesar P, Wong, Ann C Y, Gunning, Peter W, Hardeman, Edna C, Palmer, Stephen J. 2014. The role of GTF2IRD1 in the auditory pathology of Williams-Beuren Syndrome. In European journal of human genetics : EJHG, 23, 774-80. doi:10.1038/ejhg.2014.188. https://pubmed.ncbi.nlm.nih.gov/25248400/

6. Davenport, Christopher M, Teubner, Brett J W, Han, Seung Baek, Blundon, Jay A, Zakharenko, Stanislav S. 2022. Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice. In Cell, 185, 3877-3895.e21. doi:10.1016/j.cell.2022.08.022. https://pubmed.ncbi.nlm.nih.gov/36152627/