Cyp39a1-flox 基因敲除小鼠

1. Wang, Pingyi, Lu, Hongyan, Rong, Hao, He, Yongjun, Jin, Tianbo. 2023. The Association of Methylation Level in the CYP39A1 Gene with High Altitude Pulmonary Edema in the Chinese Population. In Pharmacogenomics and personalized medicine, 16, 617-628. doi:10.2147/PGPM.S397862. https://pubmed.ncbi.nlm.nih.gov/37366513/

2. Li, Zheng, Wang, Zhenxun, Lee, Mei Chin, Tam, Wai Leong, Khor, Chiea Chuen. . Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. In JAMA, 325, 753-764. doi:10.1001/jama.2021.0507. https://pubmed.ncbi.nlm.nih.gov/33620406/

3. Li, Dan, Yu, Tao, Hu, Junjie, Gu, Lijuan, Zeng, Zhi. 2021. Downregulation of CYP39A1 Serves as a Novel Biomarker in Hepatocellular Carcinoma with Worse Clinical Outcome. In Oxidative medicine and cellular longevity, 2021, 5175581. doi:10.1155/2021/5175581. https://pubmed.ncbi.nlm.nih.gov/35003516/

4. Bell, Katharina, Ozaki, Mineo, Mori, Kazuhiko, Khor, Chiea Chuen, Aung, Tin. 2021. Association of the CYP39A1 G204E Genetic Variant with Increased Risk of Glaucoma and Blindness in Patients with Exfoliation Syndrome. In Ophthalmology, 129, 406-413. doi:10.1016/j.ophtha.2021.11.001. https://pubmed.ncbi.nlm.nih.gov/34763023/

5. Kim, Ki-Hyun, Park, Young-Lan, Park, Sun-Young, Joo, Young-Eun. 2023. Expression of an oxysterol-metabolizing enzyme in colorectal cancer and its relation to tumor cell behavior and prognosis. In Pathology, research and practice, 251, 154875. doi:10.1016/j.prp.2023.154875. https://pubmed.ncbi.nlm.nih.gov/37820439/

6. Maksymchuk, Oksana, Gerashchenko, Ganna, Rosohatska, Inna, Stakhovsky, Eduard, Kashuba, Volodymyr. 2024. Cytochrome P450 genes expression in human prostate cancer. In Molecular genetics and metabolism reports, 38, 101049. doi:10.1016/j.ymgmr.2024.101049. https://pubmed.ncbi.nlm.nih.gov/38469085/

7. Matsuoka, Hiroshi, Katayama, Miyu, Ohishi, Ami, Shima, Akiho, Michihara, Akihiro. 2020. Orphan Nuclear Receptor RORα Regulates Enzymatic Metabolism of Cerebral 24S-Hydroxycholesterol through CYP39A1 Intronic Response Element Activation. In International journal of molecular sciences, 21, . doi:10.3390/ijms21093309. https://pubmed.ncbi.nlm.nih.gov/32392803/

8. Uchiyama, Toshitaka, Kanno, Hitoshi, Ishitani, Ken, Kamatani, Naoyuki, Saito, Kayoko. 2012. An SNP in CYP39A1 is associated with severe neutropenia induced by docetaxel. In Cancer chemotherapy and pharmacology, 69, 1617-24. doi:10.1007/s00280-012-1872-4. https://pubmed.ncbi.nlm.nih.gov/22562553/