Otud5-flox 基因敲除小鼠

1. Hou, Tao, Dan, Weichao, Liu, Tianjie, Fan, Yizeng, Li, Lei. 2022. Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression. In Cell death & disease, 13, 778. doi:10.1038/s41419-022-05128-6. https://pubmed.ncbi.nlm.nih.gov/36085200/

2. Yang, Yingnan, Jia, Siying, Zhu, Ning, Guo, Yong, Xu, Qiuran. 2024. OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1. In Biology direct, 19, 31. doi:10.1186/s13062-024-00475-0. https://pubmed.ncbi.nlm.nih.gov/38658981/

3. Saida, Ken, Fukuda, Tokiko, Scott, Daryl A, Miyake, Noriko, Matsumoto, Naomichi. 2021. OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation. In Frontiers in cell and developmental biology, 9, 631428. doi:10.3389/fcell.2021.631428. https://pubmed.ncbi.nlm.nih.gov/33748114/

4. Tripolszki, Kornelia, Sasaki, Erina, Hotakainen, Ronja, Reardon, William, Bertoli-Avella, Aida M. 2020. An X-linked syndrome with severe neurodevelopmental delay, hydrocephalus, and early lethality caused by a missense variation in the OTUD5 gene. In Clinical genetics, 99, 303-308. doi:10.1111/cge.13873. https://pubmed.ncbi.nlm.nih.gov/33131077/