Rps23rg1-flox 基因敲除小鼠

1. Wang, Chong, Zhang, Yuan, Zhao, Dongdong, Xu, Huaxi, Zhang, Yun-Wu. 2022. Phenazopyridine promotes RPS23RG1/Rps23rg1 transcription and ameliorates Alzheimer-associated phenotypes in mice. In Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 47, 2042-2050. doi:10.1038/s41386-022-01373-7. https://pubmed.ncbi.nlm.nih.gov/35821069/

2. Yan, Li, Chen, Yaomin, Li, Wubo, Tu, Shichun, Xu, Huaxi. 2016. RPS23RG1 reduces Aβ oligomer-induced synaptic and cognitive deficits. In Scientific reports, 6, 18668. doi:10.1038/srep18668. https://pubmed.ncbi.nlm.nih.gov/26733416/

3. Huang, Xiumei, Chen, Yaomin, Li, Wu-Bo, Xu, Huaxi, Zhang, Yun-Wu. 2010. The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation. In Human molecular genetics, 19, 3835-43. doi:10.1093/hmg/ddq302. https://pubmed.ncbi.nlm.nih.gov/20650958/

4. Zhao, Dongdong, Meng, Jian, Zhao, Yingjun, Xu, Huaxi, Zhang, Yun-Wu. 2018. RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits. In Biological psychiatry, 86, 171-184. doi:10.1016/j.biopsych.2018.08.009. https://pubmed.ncbi.nlm.nih.gov/30292394/