Mtx2-flox 基因敲除小鼠

1. Yeter Doğan, Burcu, Günay, Neslihan, Ada, Yasin, Doğan, Muhammet Ensar. 2022. A novel MTX2 gene splice site variant resulting in exon skipping, causing the recently described mandibuloacral dysplasia progeroid syndrome. In American journal of medical genetics. Part A, 191, 173-182. doi:10.1002/ajmg.a.63010. https://pubmed.ncbi.nlm.nih.gov/36269149/

2. Bruce, Ashley E E, Howley, Cristin, Dixon Fox, Monica, Ho, Robert K. . T-box gene eomesodermin and the homeobox-containing Mix/Bix gene mtx2 regulate epiboly movements in the zebrafish. In Developmental dynamics : an official publication of the American Association of Anatomists, 233, 105-14. doi:. https://pubmed.ncbi.nlm.nih.gov/15765511/

3. Elouej, Sahar, Harhouri, Karim, Le Mao, Morgane, Lévy, Nicolas, De Sandre-Giovannoli, Annachiara. 2020. Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology. In Nature communications, 11, 4589. doi:10.1038/s41467-020-18146-9. https://pubmed.ncbi.nlm.nih.gov/32917887/

4. Wilkins, Simon J, Yoong, Simon, Verkade, Heather, Heath, Joan K, Perkins, Andrew C. 2007. Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation. In Developmental biology, 314, 12-22. doi:. https://pubmed.ncbi.nlm.nih.gov/18154948/

5. Coppedè, Fabio. 2021. Mutations Involved in Premature-Ageing Syndromes. In The application of clinical genetics, 14, 279-295. doi:10.2147/TACG.S273525. https://pubmed.ncbi.nlm.nih.gov/34103969/