Tcaim-flox 基因敲除小鼠

1. Ye, Zhuo, Ren, Chuanchuan, Wang, Qingwei, Wang, Yan. 2022. A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib. In The FEBS journal, 289, 5259-5278. doi:10.1111/febs.16417. https://pubmed.ncbi.nlm.nih.gov/35238167/

2. Jiahui, Wang, Xiang, Yu, Youhuan, Zhong, Yingjie, Xu, Wen, Yang. 2025. The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism. In Molecular cell, 85, 638-651.e9. doi:10.1016/j.molcel.2025.01.006. https://pubmed.ncbi.nlm.nih.gov/39889707/

3. Vogel, Simone Z, Schlickeiser, Stephan, Jürchott, Karsten, Grütz, Gerald, Sawitzki, Birgit. 2015. TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production. In Journal of immunology (Baltimore, Md. : 1950), 194, 3136-46. doi:10.4049/jimmunol.1400713. https://pubmed.ncbi.nlm.nih.gov/25750433/