MGI:2685917Mice homozygous for a knock-out allele exhibit reduced male fertility associated with oligozoospermia, impaired acrosome reaction, decreased progressive motility, impaired in vivo fertilization, weak sperm-egg interactions, and defects in sperm energy metabolism.
1. Chen, Rui, Ma, Tingbin, Du, Shiyue, Shi, Qinghua, Liu, Jing Yu. . Impaired fertility in 4930590J08Rik mutant male mice is associated with defective sperm energy metabolism. In FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36, e22634. doi:10.1096/fj.202200805RR. https://pubmed.ncbi.nlm.nih.gov/36331537/