Thoc2-flox 基因敲除小鼠

1. Bhattacharjee, Rudrarup, Jolly, Lachlan A, Corbett, Mark A, Kumar, Raman, Gecz, Jozef. 2024. Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment. In Nature communications, 15, 1210. doi:10.1038/s41467-024-45121-5. https://pubmed.ncbi.nlm.nih.gov/38331934/

2. Chen, Yan, Chang, Li, Hu, Ling, Yarmohammadi, Hooman, Sun, Jun. 2024. Identification of a lactylation-related gene signature to characterize subtypes of hepatocellular carcinoma using bulk sequencing data. In Journal of gastrointestinal oncology, 15, 1636-1646. doi:10.21037/jgo-24-405. https://pubmed.ncbi.nlm.nih.gov/39279958/

3. Dubucs, Charlotte, Rendu, John, Michel-Calemard, Laurence, Aziza, Jacqueline, Uro-Coste, Emmanuelle. 2023. Muscular phenotype description of abnormal THOC2 splicing. In Neuromuscular disorders : NMD, 33, 978-982. doi:10.1016/j.nmd.2023.09.009. https://pubmed.ncbi.nlm.nih.gov/37945483/

4. Tamhankar, Vasundhara, Tamhankar, Parag, Chaubal, Rajas, Chaubal, Jyoti, Chaubal, Nitin. 2021. Novel Consensus Splice Site Pathogenic Variation in THOC2 Gene Leads to Recurrent Arthrogryposis Multiplex Congenita Phenotype: A Case Report. In Cureus, 13, e19682. doi:10.7759/cureus.19682. https://pubmed.ncbi.nlm.nih.gov/34976470/

5. Zhou, Xiaowei, Liu, Xing, Zhang, Guoqiang, Fang, Fang, Sun, Jianfang. . Knockdown THOC2 suppresses the proliferation and invasion of melanoma. In Bioengineered, 10, 635-645. doi:10.1080/21655979.2019.1685727. https://pubmed.ncbi.nlm.nih.gov/31680623/