智鼠故事 
Fto-flox 基因敲除小鼠
复苏/繁育服务
产品名称
Fto-flox 基因敲除小鼠
产品编号
S-CKO-09550
品系全称
C57BL/6NCya-Ftoem1flox/Cya
品系背景
C57BL/6NCya
品系编号
CKOCMP-26383-Fto-B6N-VA
品系状态
使用本品系发表的文献需注明： Fto-flox 基因敲除小鼠 mice (Strain S-CKO-09550) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
mKIAA1752
NCBI ID
染色体号
Chr 8
NCBI RefSeq
NM_011936
Ensembl ID
ENSMUST00000069718
修饰方式
条件性基因敲除
靶向范围
Exon 3
敲除长度
~1.5 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:1347093Mice homozygous for an ENU-induced or targeted knock-out allele exhibit decreased body weight, adipose tissue, and body fat and increased metabolism, serum lipids, and serum glucagon that may be gender and diet dependent.
发表文献
Experimental & Molecular Medicine
2024-10-03
FTO-mediated SMAD2 m6A modification protects cartilage against Osteoarthritis
Ecotoxicology and Environmental Safety
2024-03-01
Oxidative stress-mediated activation of FTO exacerbates impairment of the epithelial barrier by up-regulating IKBKB via N6-methyladenosine-dependent mRNA stability in asthmatic mice exposed to PM2.5
The Journal of Nutritional Biochemistry
2023-10-30
Hypothalamic FTO promotes high-fat diet-induced leptin resistance in mice through increasing CX3CL1 expression
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