Helt-flox 基因敲除小鼠

1. Nakatani, Tomoya, Minaki, Yasuko, Kumai, Minoru, Ono, Yuichi. 2007. Helt determines GABAergic over glutamatergic neuronal fate by repressing Ngn genes in the developing mesencephalon. In Development (Cambridge, England), 134, 2783-93. doi:. https://pubmed.ncbi.nlm.nih.gov/17611227/

2. Song, Hobeom, Lee, Bumwhee, Pyun, Dohoon, Wurst, Wolfgang, Jeong, Yongsu. 2014. Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. In Developmental biology, 398, 280-91. doi:10.1016/j.ydbio.2014.12.003. https://pubmed.ncbi.nlm.nih.gov/25512300/

3. Nakatani, Tomoya, Mizuhara, Eri, Minaki, Yasuko, Sakamoto, Yoshimasa, Ono, Yuichi. 2004. Helt, a novel basic-helix-loop-helix transcriptional repressor expressed in the developing central nervous system. In The Journal of biological chemistry, 279, 16356-67. doi:. https://pubmed.ncbi.nlm.nih.gov/14764602/

4. Maeda, Yukihide, Kariya, Shin, Uraguchi, Kensuke, Sugaya, Akiko, Nishizaki, Kazunori. 2020. Immediate changes in transcription factors and synaptic transmission in the cochlea following acoustic trauma: A gene transcriptome study. In Neuroscience research, 165, 6-13. doi:10.1016/j.neures.2020.05.001. https://pubmed.ncbi.nlm.nih.gov/32417196/

5. Tran, Hong-Nhung, Nguyen, Quy-Hoai, Jeong, Yongsu. 2024. Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi. In Frontiers in cell and developmental biology, 12, 1336308. doi:10.3389/fcell.2024.1336308. https://pubmed.ncbi.nlm.nih.gov/38344749/