Gpr171-flox 基因敲除小鼠

1. Fujiwara, Yuki, Torphy, Robert J, Sun, Yi, Schulick, Richard D, Zhu, Yuwen. 2021. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. In Nature communications, 12, 5857. doi:10.1038/s41467-021-26135-9. https://pubmed.ncbi.nlm.nih.gov/34615877/

2. Ram, Akila, Edwards, Taylor, McCarty, Ashley, McDermott, Max V, Bobeck, Erin N. 2021. GPR171 Agonist Reduces Chronic Neuropathic and Inflammatory Pain in Male, But Not Female Mice. In Frontiers in pain research (Lausanne, Switzerland), 2, 695396. doi:10.3389/fpain.2021.695396. https://pubmed.ncbi.nlm.nih.gov/35295419/

3. McDermott, Max V, Ram, Akila, Mattoon, Matthew T, Thomason, Madi K, Bobeck, Erin N. 2023. A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice. In Pharmacology, biochemistry, and behavior, 224, 173543. doi:10.1016/j.pbb.2023.173543. https://pubmed.ncbi.nlm.nih.gov/36933620/

4. Dai, Ji, Chen, Qi, Li, Guoqing, Sun, Haohang, Yan, Meidi. 2022. DIRAS3, GPR171 and RAC2 were identified as the key molecular patterns associated with brain metastasis of breast cancer. In Frontiers in oncology, 12, 965136. doi:10.3389/fonc.2022.965136. https://pubmed.ncbi.nlm.nih.gov/36212434/

5. Rossi, Lara, Lemoli, Roberto M, Goodell, Margaret A. 2012. Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors. In Experimental hematology, 41, 102-12. doi:10.1016/j.exphem.2012.09.007. https://pubmed.ncbi.nlm.nih.gov/23022127/

6. Wardman, Jonathan H, Gomes, Ivone, Bobeck, Erin N, Filizola, Marta, Devi, Lakshmi A. 2016. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. In Science signaling, 9, ra55. doi:10.1126/scisignal.aac8035. https://pubmed.ncbi.nlm.nih.gov/27245612/

7. Aryal, Dipendra K, Rodriguiz, Ramona M, Nguyen, Ngoc Lien, Fricker, Lloyd D, Wetsel, William C. 2022. Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment. In Genes, brain, and behavior, 21, e12827. doi:10.1111/gbb.12827. https://pubmed.ncbi.nlm.nih.gov/35878875/

8. Wu, Zhuoyi, Wan, Jinghai, Wang, Jiawei, Meng, Xiaoli, Qian, Haipeng. 2022. Identification of prognostic biomarkers for breast cancer brain metastases based on the bioinformatics analysis. In Biochemistry and biophysics reports, 29, 101203. doi:10.1016/j.bbrep.2022.101203. https://pubmed.ncbi.nlm.nih.gov/35059509/

9. Yin, Guicao, Zheng, Shengqi, Zhang, Wei, Qi, Lezhong, Li, Yifan. 2023. Classification of bladder cancer based on immune cell infiltration and construction of a risk prediction model for prognosis. In Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 53, 47-57. doi:10.3724/zdxbyxb-2023-0343. https://pubmed.ncbi.nlm.nih.gov/38229504/