Cerkl-flox 基因敲除小鼠

1. García-Arroyo, Rocío, Marfany, Gemma, Mirra, Serena. 2022. CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons. In International journal of molecular sciences, 23, . doi:10.3390/ijms231911593. https://pubmed.ncbi.nlm.nih.gov/36232896/

2. Mirra, Serena, García-Arroyo, Rocío, B Domènech, Elena, Villarroya, Francesc, Marfany, Gemma. 2021. CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina. In Neurobiology of disease, 156, 105405. doi:10.1016/j.nbd.2021.105405. https://pubmed.ncbi.nlm.nih.gov/34048907/

3. Yu, Shanshan, Li, Chang, Biswas, Lincoln, Tang, Zhaohui, Liu, Mugen. . CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish. In Human molecular genetics, 26, 2335-2345. doi:10.1093/hmg/ddx137. https://pubmed.ncbi.nlm.nih.gov/28398482/

4. Hu, Xuebin, Lu, Zhaojing, Yu, Shanshan, Tang, Zhaohui, Liu, Mugen. 2018. CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1. In Autophagy, 15, 453-465. doi:10.1080/15548627.2018.1520548. https://pubmed.ncbi.nlm.nih.gov/30205735/