Impg2-flox 基因敲除小鼠

1. Xu, Rong, Wang, Yekai, Du, Jianhai, Salido, Ezequiel M. . Retinal Metabolic Profile on IMPG2 Deficiency Mice with Subretinal Lesions. In Advances in experimental medicine and biology, 1415, 457-463. doi:10.1007/978-3-031-27681-1_67. https://pubmed.ncbi.nlm.nih.gov/37440072/

2. Mayerl, Steven J, Bajgai, Simona, Ludwig, Allison L, Philpot, Benjamin D, Gamm, David M. 2022. Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa. In Stem cell reports, 17, 2409-2420. doi:10.1016/j.stemcr.2022.09.004. https://pubmed.ncbi.nlm.nih.gov/36206764/

3. van Huet, Ramon A C, Collin, Rob W J, Siemiatkowska, Anna M, van den Born, L Ingeborgh, Klevering, B Jeroen. 2014. IMPG2-associated retinitis pigmentosa displays relatively early macular involvement. In Investigative ophthalmology & visual science, 55, 3939-53. doi:10.1167/iovs.14-14129. https://pubmed.ncbi.nlm.nih.gov/24876279/

4. Xu, Huijuan, Qu, Chao, Gan, Li, Zhu, Xianjun, Zhang, Lin. . Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice. In Human molecular genetics, 29, 1624-1634. doi:10.1093/hmg/ddaa062. https://pubmed.ncbi.nlm.nih.gov/32242237/