U2af2-flox 基因敲除小鼠

1. Wang, Xiaole, You, Baiyang, Yin, Fei, Pang, Nan, Peng, Jing. 2023. A presumed missense variant in the U2AF2 gene causes exon skipping in neurodevelopmental diseases. In Journal of human genetics, 68, 375-382. doi:10.1038/s10038-023-01128-2. https://pubmed.ncbi.nlm.nih.gov/36747105/

2. Maji, Debanjana, Glasser, Eliezra, Henderson, Steven, Jenkins, Jermaine L, Kielkopf, Clara L. 2020. Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. In The Journal of biological chemistry, 295, 17148-17157. doi:10.1074/jbc.RA120.015339. https://pubmed.ncbi.nlm.nih.gov/33020180/

3. Li, Jing, Cheng, Dongdong, Zhu, Miaoxin, Yan, Mingxia, Yao, Ming. 2019. OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer. In Theranostics, 9, 179-195. doi:10.7150/thno.29545. https://pubmed.ncbi.nlm.nih.gov/30662561/

4. Zhang, Wenrong, Song, Xinyue, Jin, Zining, Jin, Feng, Zheng, Ang. 2024. U2AF2-SNORA68 promotes triple-negative breast cancer stemness through the translocation of RPL23 from nucleoplasm to nucleolus and c-Myc expression. In Breast cancer research : BCR, 26, 60. doi:10.1186/s13058-024-01817-6. https://pubmed.ncbi.nlm.nih.gov/38594783/