Usp43-flox 基因敲除小鼠

1. Pauzaite, Tekle, Wit, Niek, Seear, Rachel V, Nathan, James A. 2024. Deubiquitinating enzyme mutagenesis screens identify a USP43-dependent HIF-1 transcriptional response. In The EMBO journal, 43, 3677-3709. doi:10.1038/s44318-024-00166-6. https://pubmed.ncbi.nlm.nih.gov/39009674/

2. Li, Qin, Li, Wenhao, Wang, Jiahao, Shi, Wenjing, Wang, Taorong. 2024. Effect of ubiquitin-specific proteinase 43 on ovarian serous adenocarcinoma and its clinical significance. In Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 44, 2361862. doi:10.1080/01443615.2024.2361862. https://pubmed.ncbi.nlm.nih.gov/38916982/

3. Pei, Lipeng, Zhao, Feng, Zhang, Yi. 2023. USP43 impairs cisplatin sensitivity in epithelial ovarian cancer through HDAC2-dependent regulation of Wnt/β-catenin signaling pathway. In Apoptosis : an international journal on programmed cell death, 29, 210-228. doi:10.1007/s10495-023-01873-x. https://pubmed.ncbi.nlm.nih.gov/38087046/

4. Zhang, Yanhua, Liu, Yujing, Deng, Qicheng, Liu, Lifen, Zhu, Weipei. 2025. USP43 drives cervical carcinoma progression through regulation of the Hippo/TAZ pathway. In International immunopharmacology, 149, 114217. doi:10.1016/j.intimp.2025.114217. https://pubmed.ncbi.nlm.nih.gov/39922114/

5. He, Lin, Liu, Xinhua, Yang, Jianguo, Sun, Luyang, Shang, Yongfeng. 2018. Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis. In Cell research, 28, 934-951. doi:10.1038/s41422-018-0079-6. https://pubmed.ncbi.nlm.nih.gov/30135474/

6. Zhong, Rong, He, Heng, Jin, Meng, Miao, Xiaoping, Tian, Jianbo. 2021. Genome-wide gene-bisphenol A, F and triclosan interaction analyses on urinary oxidative stress markers. In The Science of the total environment, 807, 150753. doi:10.1016/j.scitotenv.2021.150753. https://pubmed.ncbi.nlm.nih.gov/34619205/

7. Mohamadipoor Saadatabadi, Leila, Mohammadabadi, Mohammadreza, Amiri Ghanatsaman, Zeinab, Kochuk-Yashchenko, Oleksandr, Asadollahpour Nanaei, Hojjat. 2021. Signature selection analysis reveals candidate genes associated with production traits in Iranian sheep breeds. In BMC veterinary research, 17, 369. doi:10.1186/s12917-021-03077-4. https://pubmed.ncbi.nlm.nih.gov/34861880/

8. Lavaud, Mélanie, Mullard, Mathilde, Tesfaye, Robel, Rédini, Françoise, Verrecchia, Franck. 2021. Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619. In Cells, 10, . doi:10.3390/cells10092268. https://pubmed.ncbi.nlm.nih.gov/34571917/