Socs2-flox 基因敲除小鼠

1. Chen, Qianping, Zheng, Wang, Guan, Jian, Zhang, Jianghong, Shao, Chunlin. 2022. SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma. In Cell death and differentiation, 30, 137-151. doi:10.1038/s41418-022-01051-7. https://pubmed.ncbi.nlm.nih.gov/35995846/

2. Chen, S-S, Wu, W-Z, Zhang, Y-P, Huang, W-J. . Gene polymorphisms of SOCS1 and SOCS2 and acute lymphoblastic leukemia. In European review for medical and pharmacological sciences, 24, 5564-5572. doi:10.26355/eurrev_202005_21342. https://pubmed.ncbi.nlm.nih.gov/32495891/

3. Grandits, Alexander M, Wieser, Rotraud. 2021. Gene expression changes contribute to stemness and therapy resistance of relapsed acute myeloid leukemia: roles of SOCS2, CALCRL, MTSS1, and KDM6A. In Experimental hematology, 99, 1-11. doi:10.1016/j.exphem.2021.05.004. https://pubmed.ncbi.nlm.nih.gov/34029637/

4. Cai, Songhua, Zhang, Baohui, Huang, Chujian, Ma, Kai, Yu, Zhentao. 2023. CTRP6 protects against ferroptosis to drive lung cancer progression and metastasis by destabilizing SOCS2 and augmenting the xCT/GPX4 pathway. In Cancer letters, 579, 216465. doi:10.1016/j.canlet.2023.216465. https://pubmed.ncbi.nlm.nih.gov/38084702/

5. Nguyen, Chi Huu, Glüxam, Tobias, Schlerka, Angela, Wieser, Rotraud, Heller, Gerwin. 2019. SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness. In Scientific reports, 9, 9139. doi:10.1038/s41598-019-45579-0. https://pubmed.ncbi.nlm.nih.gov/31235852/