Chadl-flox 基因敲除小鼠

1. Tillgren, Viveka, Ho, James C S, Önnerfjord, Patrik, Kalamajski, Sebastian. 2014. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentiation. In The Journal of biological chemistry, 290, 918-25. doi:10.1074/jbc.M114.593541. https://pubmed.ncbi.nlm.nih.gov/25451920/

2. Styrkarsdottir, Unnur, Helgason, Hannes, Sigurdsson, Asgeir, Thorsteinsdottir, Unnur, Stefansson, Kari. 2017. Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis. In Nature genetics, 49, 801-805. doi:10.1038/ng.3816. https://pubmed.ncbi.nlm.nih.gov/28319091/

3. Herkiloglu, Dilsad, Gokce, Sefik, Gumus, Erkan, Kaygusuz, Ecmel Isik, Cevik, Ozge. . Chondoadherin as a biomarker in patients with endometrial cancer. In Annali italiani di chirurgia, 92, 325-330. doi:. https://pubmed.ncbi.nlm.nih.gov/36052469/

4. Tuerlings, Margo, van Hoolwerff, Marcella, Houtman, Evelyn, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid. 2021. RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets. In Arthritis & rheumatology (Hoboken, N.J.), 73, 789-799. doi:10.1002/art.41600. https://pubmed.ncbi.nlm.nih.gov/33258547/

5. Bourne, Lucie E, Hesketh, Andrew, Sharma, Aikta, Bush, Peter G, Staines, Katherine A. 2023. The effects of physiological and injurious hydrostatic pressure on murine ex vivo articular and growth plate cartilage explants: an RNAseq study. In Frontiers in endocrinology, 14, 1278596. doi:10.3389/fendo.2023.1278596. https://pubmed.ncbi.nlm.nih.gov/38144567/

6. Borczyk, Malgorzata, Fichna, Jakub P, Piechota, Marcin, Janik, Piotr, Żekanowski, Cezary. 2025. Oligogenic risk score for Gilles de la Tourette syndrome reveals a genetic continuum of tic disorders. In Journal of applied genetics, , . doi:10.1007/s13353-024-00930-8. https://pubmed.ncbi.nlm.nih.gov/39792217/

7. Liu, Yifan, Tu, Yunjie, Zhang, Ming, Shu, Jingting, Zou, Jianmin. 2018. Identification of molecular pathways and candidate genes associated with cocks' comb size trait by genome-wide transcriptome analysis. In Scientific reports, 8, 2015. doi:10.1038/s41598-018-20373-6. https://pubmed.ncbi.nlm.nih.gov/29386544/

8. de Oliveira, Haniel Cedraz, Ibelli, Adriana Mércia Guaratini, Guimarães, Simone Eliza Facioni, Coutinho, Luiz Lehmann, Ledur, Mônica Corrêa. 2020. RNA-seq reveals downregulated osteochondral genes potentially related to tibia bacterial chondronecrosis with osteomyelitis in broilers. In BMC genetics, 21, 58. doi:10.1186/s12863-020-00862-2. https://pubmed.ncbi.nlm.nih.gov/32493207/

9. Styrkarsdottir, Unnur, Lund, Sigrun H, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Stefansson, Kari. 2018. Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. In Nature genetics, 50, 1681-1687. doi:10.1038/s41588-018-0247-0. https://pubmed.ncbi.nlm.nih.gov/30374069/