Tmie-flox 基因敲除小鼠

1. Rayat, Sima, Farhadi, Mohammad, Emamdjomeh, Hessamaldin, Morovvati, Saeid, Falah, Masoumeh. 2022. Analysis of TMIE gene mutations including the first large deletion of exon 1 with autosomal recessive non-syndromic deafness. In BMC medical genomics, 15, 133. doi:10.1186/s12920-022-01287-9. https://pubmed.ncbi.nlm.nih.gov/35710363/

2. Mitchem, Kristina L, Hibbard, Ellen, Beyer, Lisa A, Raphael, Yehoash, Kohrman, David C. . Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6. In Human molecular genetics, 11, 1887-98. doi:. https://pubmed.ncbi.nlm.nih.gov/12140191/

3. Naz, Sadaf, Giguere, Chantal M, Kohrman, David C, Smith, Richard J H, Wilcox, Edward R. 2002. Mutations in a novel gene, TMIE, are associated with hearing loss linked to the DFNB6 locus. In American journal of human genetics, 71, 632-6. doi:. https://pubmed.ncbi.nlm.nih.gov/12145746/

4. Santos, Regie Lyn P, El-Shanti, Hatem, Sikandar, Shaheen, Ahmad, Wasim, Leal, Suzanne M. 2005. Novel sequence variants in the TMIE gene in families with autosomal recessive nonsyndromic hearing impairment. In Journal of molecular medicine (Berlin, Germany), 84, 226-31. doi:. https://pubmed.ncbi.nlm.nih.gov/16389551/

5. Shen, Yu-Chi, Jeyabalan, Anandhi K, Wu, Karen L, Liu, Dong, Barald, Kate F. . The transmembrane inner ear (tmie) gene contributes to vestibular and lateral line development and function in the zebrafish (Danio rerio). In Developmental dynamics : an official publication of the American Association of Anatomists, 237, 941-52. doi:10.1002/dvdy.21486. https://pubmed.ncbi.nlm.nih.gov/18330929/

6. Shin, Mi Jung, Lee, Jeong-Han, Yu, Dong Hoon, Park, Raekil, Ryoo, Zae Young. . Spatiotemporal expression of tmie in the inner ear of rats during postnatal development. In Comparative medicine, 60, 288-94. doi:. https://pubmed.ncbi.nlm.nih.gov/20819378/

7. Yang, Jiann-Jou, Su, Mao-Chang, Chien, Kuo-Hsuan, Hsin, Chung-Han, Li, Shuan-Yow. 2010. Identification of novel variants in the TMIE gene of patients with nonsyndromic hearing loss. In International journal of pediatric otorhinolaryngology, 74, 489-93. doi:10.1016/j.ijporl.2010.02.001. https://pubmed.ncbi.nlm.nih.gov/20206386/

8. Zhao, Bo, Wu, Zizhen, Grillet, Nicolas, Harkins-Perry, Sarah, Müller, Ulrich. 2014. TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells. In Neuron, 84, 954-67. doi:10.1016/j.neuron.2014.10.041. https://pubmed.ncbi.nlm.nih.gov/25467981/

9. Park, Seojin, Lee, Jeong-Han, Cho, Hyun-Ju, Yun, Byung-Wook, Ryoo, ZaeYoung. . tmie Is required for gentamicin uptake by the hair cells of mice. In Comparative medicine, 63, 136-42. doi:. https://pubmed.ncbi.nlm.nih.gov/23582420/

10. Shin, Mi Jung, Lee, Jeong-Han, Yu, Dong Hoon, Park, Raekil, Ryoo, Zae Young. 2008. Ectopic expression of tmie transgene induces various recovery levels of behavior and hearing ability in the circling mouse. In Biochemical and biophysical research communications, 374, 17-21. doi:10.1016/j.bbrc.2008.06.064. https://pubmed.ncbi.nlm.nih.gov/18586001/