Xpr1-flox 基因敲除小鼠

1. Anheim, Mathieu, López-Sánchez, Uriel, Giovannini, Donatella, Sitbon, Marc, Nicolas, Gaël. 2016. XPR1 mutations are a rare cause of primary familial brain calcification. In Journal of neurology, 263, 1559-64. doi:10.1007/s00415-016-8166-4. https://pubmed.ncbi.nlm.nih.gov/27230854/

2. Mao, Xiaohuan, Guo, Shuren, Gao, Lan, Li, Gang. 2020. Circ-XPR1 promotes osteosarcoma proliferation through regulating the miR-214-5p/DDX5 axis. In Human cell, 34, 122-131. doi:10.1007/s13577-020-00412-z. https://pubmed.ncbi.nlm.nih.gov/32920730/

3. Barker, Christopher J, Tessaro, Fernando Henrique Galvão, Ferreira, Sabrina de Souza, Darè, Elisabetta, Berggren, Per-Olof. 2020. XPR1 Mediates the Pancreatic β-Cell Phosphate Flush. In Diabetes, 70, 111-118. doi:10.2337/db19-0633. https://pubmed.ncbi.nlm.nih.gov/32826297/

4. Liao, Zi-Qiang, Lv, Yang-Feng, Kang, Mei-Diao, Yi, Yun, Tang, Qun. 2024. Inhibition of XPR1-dependent phosphate efflux induces mitochondrial dysfunction: A potential molecular target therapy for hepatocellular carcinoma? In Molecular carcinogenesis, 63, 2332-2345. doi:10.1002/mc.23812. https://pubmed.ncbi.nlm.nih.gov/39136583/

5. Legati, Andrea, Giovannini, Donatella, Nicolas, Gaël, Battini, Jean-Luc, Coppola, Giovanni. 2015. Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. In Nature genetics, 47, 579-81. doi:10.1038/ng.3289. https://pubmed.ncbi.nlm.nih.gov/25938945/