Rad17-flox 基因敲除小鼠

1. Sun, Jingkai, Lin, Wenfeng, Wang, Qixu, Xu, Abai, Huang, Peng. . The Cell Cycle Checkpoint Gene, RAD17 rs1045051, Is Associated with Prostate Cancer Risk. In Acta medica Okayama, 75, 415-421. doi:10.18926/AMO/62379. https://pubmed.ncbi.nlm.nih.gov/34511607/

2. Joris, Sofie, Giron, Philippe, Olsen, Catharina, De Grève, Jacques, Hes, Frederik J. 2024. Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers. In BMC cancer, 24, 723. doi:10.1186/s12885-024-12442-z. https://pubmed.ncbi.nlm.nih.gov/38872153/

3. Valenti, Fabio, Ganci, Federica, Fontemaggi, Giulia, Blandino, Giovanni, Di Agostino, Silvia. . Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression. In Oncotarget, 6, 5547-66. doi:. https://pubmed.ncbi.nlm.nih.gov/25650659/

4. Zhu, Judy, Fleming, Aaron M, Burrows, Cynthia J. 2018. The RAD17 Promoter Sequence Contains a Potential Tail-Dependent G-Quadruplex That Downregulates Gene Expression upon Oxidative Modification. In ACS chemical biology, 13, 2577-2584. doi:10.1021/acschembio.8b00522. https://pubmed.ncbi.nlm.nih.gov/30063821/

5. Nishino, Katsuaki, Inoue, Eri, Takada, Shunya, Seki, Masayuki, Enomoto, Takemi. . A novel role for Rad17 in homologous recombination. In Genes & genetic systems, 83, 427-31. doi:. https://pubmed.ncbi.nlm.nih.gov/19168994/