Myt1l-flox 基因敲除小鼠

1. Chen, Jiayang, Yen, Allen, Florian, Colin P, Dougherty, Joseph D. 2022. MYT1L in the making: emerging insights on functions of a neurodevelopmental disorder gene. In Translational psychiatry, 12, 292. doi:10.1038/s41398-022-02058-x. https://pubmed.ncbi.nlm.nih.gov/35869058/

2. Weigel, Bettina, Tegethoff, Jana F, Grieder, Sarah D, Acuna, Claudio, Mall, Moritz. 2023. MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention. In Molecular psychiatry, 28, 2122-2135. doi:10.1038/s41380-023-01959-7. https://pubmed.ncbi.nlm.nih.gov/36782060/

3. D'Agnelli, Simona, Arendt-Nielsen, Lars, Gerra, Maria C, Baciarello, Marco, Bignami, Elena. 2018. Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers. In Molecular pain, 15, 1744806918819944. doi:10.1177/1744806918819944. https://pubmed.ncbi.nlm.nih.gov/30486733/

4. Chen, Jiayang, Fuhler, Nicole A, Noguchi, Kevin K, Dougherty, Joseph D. 2023. MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain. In Genome research, 33, 541-556. doi:10.1101/gr.277413.122. https://pubmed.ncbi.nlm.nih.gov/37100461/

5. Yen, Allen, Chen, Xuhua, Skinner, Dominic D, Mitra, Robi D, Dougherty, Joseph D. 2024. MYT1L deficiency impairs excitatory neuron trajectory during cortical development. In bioRxiv : the preprint server for biology, , . doi:10.1101/2024.03.06.583632. https://pubmed.ncbi.nlm.nih.gov/38496654/