Mns1-flox 基因敲除小鼠

1. Maraval, Julien, Delahaye-Duriez, Andrée, Racine, Caroline, Keren, Boris, Faivre, Laurence. 2024. Expanding MNS1 Heterotaxy Phenotype. In American journal of medical genetics. Part A, 197, e63862. doi:10.1002/ajmg.a.63862. https://pubmed.ncbi.nlm.nih.gov/39233552/

2. Hjeij, Rim, Leslie, Joseph, Rizk, Hoda, Baple, Emma, Omran, Heymut. 2024. Biallelic Variants in MNS1 Are Associated with Laterality Defects and Respiratory Involvement. In Cells, 13, . doi:10.3390/cells13121017. https://pubmed.ncbi.nlm.nih.gov/38920647/

3. Yi, Yong, Yu, Min-Cheng, Fu, Pei-Yao, Sun, Bao-Ye, Qiu, Shuang-Jian. 2021. MNS1 promotes hepatocarcinogenesis and metastasis via activating PI3K/AKT by translocating β-catenin and predicts poor prognosis. In Liver international : official journal of the International Association for the Study of the Liver, 41, 1409-1420. doi:10.1111/liv.14803. https://pubmed.ncbi.nlm.nih.gov/33506565/

4. Ta-Shma, Asaf, Hjeij, Rim, Perles, Zeev, Elpeleg, Orly, Omran, Heymut. 2018. Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility. In PLoS genetics, 14, e1007602. doi:10.1371/journal.pgen.1007602. https://pubmed.ncbi.nlm.nih.gov/30148830/