Mapkapk2-flox 基因敲除小鼠

1. Coelho, Matthew A, de Carné Trécesson, Sophie, Rana, Sareena, Blackshear, Perry J, Downward, Julian. 2017. Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA. In Immunity, 47, 1083-1099.e6. doi:10.1016/j.immuni.2017.11.016. https://pubmed.ncbi.nlm.nih.gov/29246442/

2. Menon, Manoj B, Gaestel, Matthias. 2017. MK2-TNF-Signaling Comes Full Circle. In Trends in biochemical sciences, 43, 170-179. doi:10.1016/j.tibs.2017.12.002. https://pubmed.ncbi.nlm.nih.gov/29275999/

3. Wang, Rui, Liu, Hongwei, Shao, Yingying, Gao, Xiumei, Yu, Haiyang. 2019. Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2. In Molecular cancer research : MCR, 17, 2469-2479. doi:10.1158/1541-7786.MCR-19-0553. https://pubmed.ncbi.nlm.nih.gov/31575657/

4. Soni, Sourabh, Anand, Prince, Swarnkar, Mohit Kumar, Tirpude, Narendra V, Padwad, Yogendra S. 2023. MAPKAPK2-centric transcriptome profiling reveals its major role in governing molecular crosstalk of IGFBP2, MUC4, and PRKAR2B during HNSCC pathogenesis. In Computational and structural biotechnology journal, 21, 1292-1311. doi:10.1016/j.csbj.2023.01.039. https://pubmed.ncbi.nlm.nih.gov/36817960/