Epn2-flox 基因敲除小鼠

1. Sakai, Eiko, Miura, Yusuke, Suzuki-Kouyama, Emi, Sakurai, Fuminori, Mizuguchi, Hiroyuki. 2017. A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2. In Scientific reports, 7, 5541. doi:10.1038/s41598-017-05782-3. https://pubmed.ncbi.nlm.nih.gov/28717225/

2. Tessneer, Kandice L, Pasula, Satish, Cai, Xiaofeng, Adams, Ralf H, Chen, Hong. 2013. Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency. In Arteriosclerosis, thrombosis, and vascular biology, 34, 331-337. doi:10.1161/ATVBAHA.113.302586. https://pubmed.ncbi.nlm.nih.gov/24311377/

3. Chen, Hong, Ko, Genevieve, Zatti, Alessandra, De Camilli, Pietro, Cremona, Ottavio. 2009. Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. In Proceedings of the National Academy of Sciences of the United States of America, 106, 13838-43. doi:10.1073/pnas.0907008106. https://pubmed.ncbi.nlm.nih.gov/19666558/

4. Mo, Jinggang, Li, Bo, Zhou, Yong, Wu, Xiaoyu, Zhang, Yaqiong. 2019. LINC00473 promotes hepatocellular carcinoma progression via acting as a ceRNA for microRNA-195 and increasing HMGA2 expression. In Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 120, 109403. doi:10.1016/j.biopha.2019.109403. https://pubmed.ncbi.nlm.nih.gov/31562977/