Dgcr6-flox 基因敲除小鼠

1. Lindsay, E A, Baldini, A. . A mouse gene (Dgcr6) related to the Drosophila gonadal gene is expressed in early embryogenesis and is the homolog of a human gene deleted in DiGeorge syndrome. In Cytogenetics and cell genetics, 79, 243-7. doi:. https://pubmed.ncbi.nlm.nih.gov/9605865/

2. Hierck, Beerend P, Molin, Danil G M, Boot, Marit J, Poelmann, Robert E, Gittenberger-de Groot, Adriana C. . A chicken model for DGCR6 as a modifier gene in the DiGeorge critical region. In Pediatric research, 56, 440-8. doi:. https://pubmed.ncbi.nlm.nih.gov/15333760/

3. Edelmann, L, Stankiewicz, P, Spiteri, E, Lupski, J R, Morrow, B E. . Two functional copies of the DGCR6 gene are present on human chromosome 22q11 due to a duplication of an ancestral locus. In Genome research, 11, 208-17. doi:. https://pubmed.ncbi.nlm.nih.gov/11157784/

4. Richard, Anne Claire, Rovelet-Lecrux, Anne, Delaby, Elsa, Betancur, Catalina, Campion, Dominique. 2016. The 22q11 PRODH/DGCR6 deletion is frequent in hyperprolinemic subjects but is not a strong risk factor for ASD. In American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 171B, 377-82. doi:10.1002/ajmg.b.32416. https://pubmed.ncbi.nlm.nih.gov/26978485/

5. Zamariolli, Malú, Auwerx, Chiara, Sadler, Marie C, Melaragno, Maria Isabel, Kutalik, Zoltán. 2023. The impact of 22q11.2 copy-number variants on human traits in the general population. In American journal of human genetics, 110, 300-313. doi:10.1016/j.ajhg.2023.01.005. https://pubmed.ncbi.nlm.nih.gov/36706759/

6. Gao, Wenming, Higaki, Takashi, Eguchi-Ishimae, Minenori, Ishii, Eiichi, Eguchi, Mariko. 2015. DGCR6 at the proximal part of the DiGeorge critical region is involved in conotruncal heart defects. In Human genome variation, 2, 15004. doi:10.1038/hgv.2015.4. https://pubmed.ncbi.nlm.nih.gov/27081520/

7. Das Chakraborty, R, Bernal, A J, Schoch, K, Jirtle, R L, Shashi, V. 2012. Dysregulation of DGCR6 and DGCR6L: psychopathological outcomes in chromosome 22q11.2 deletion syndrome. In Translational psychiatry, 2, e105. doi:10.1038/tp.2012.31. https://pubmed.ncbi.nlm.nih.gov/22832905/

8. Pfuhl, Thorsten, Dürr, Matthias, Spurk, Andreas, Kremmer, Elisabeth, Grässer, Friedrich A. 2005. Biochemical characterisation of the proteins encoded by the DiGeorge critical region 6 (DGCR6) genes. In Human genetics, 117, 70-80. doi:. https://pubmed.ncbi.nlm.nih.gov/15821931/

9. Muntyanu, Anastasiya, Le, Michelle, Ridha, Zainab, Lefrançois, Philippe, Netchiporouk, Elena. 2021. Novel role of long non-coding RNAs in autoimmune cutaneous disease. In Journal of cell communication and signaling, 16, 487-504. doi:10.1007/s12079-021-00639-x. https://pubmed.ncbi.nlm.nih.gov/34346026/