Cdc42-flox 基因敲除小鼠

1. Nicole, S, White, P S, Topaloglu, H, Hentati, F, Fontaine, B. . The human CDC42 gene: genomic organization, evidence for the existence of a putative pseudogene and exclusion as a SJS1 candidate gene. In Human genetics, 105, 98-103. doi:. https://pubmed.ncbi.nlm.nih.gov/10480361/

2. Yang, Linda, Wang, Lei, Zheng, Yi. 2006. Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. In Molecular biology of the cell, 17, 4675-85. doi:. https://pubmed.ncbi.nlm.nih.gov/16914516/

3. Stengel, Kristy R, Zheng, Yi. 2012. Essential role of Cdc42 in Ras-induced transformation revealed by gene targeting. In PloS one, 7, e37317. doi:10.1371/journal.pone.0037317. https://pubmed.ncbi.nlm.nih.gov/22719838/

4. Valdés-Mora, Fatima, Locke, Warwick J, Bandrés, Eva, Del Pulgar, Teresa Gómez, Lacal, Juan Carlos. . Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer. In Oncotarget, 8, 26755-26770. doi:10.18632/oncotarget.15815. https://pubmed.ncbi.nlm.nih.gov/28460460/