Adora1-flox 基因敲除小鼠

1. Pan, Suming, Liang, Sixian, Wang, Xianyan. 2021. ADORA1 promotes nasopharyngeal carcinoma cell progression through regulation of PI3K/AKT/GSK-3β/β-catenin signaling. In Life sciences, 278, 119581. doi:10.1016/j.lfs.2021.119581. https://pubmed.ncbi.nlm.nih.gov/33961854/

2. Lin, Xu, Wang, Zhi-Yong, Xue, Gang, Wu, Jing-Fang, Zhang, Geng. 2021. ADORA1 is a diagnostic-related biomarker and correlated with immune infiltrates in papillary thyroid carcinoma. In Journal of Cancer, 12, 3997-4010. doi:10.7150/jca.50743. https://pubmed.ncbi.nlm.nih.gov/34093805/

3. Jaberi, Elham, Rohani, Mohammad, Shahidi, Gholam Ali, Steemers, Frank, Elahi, Elahe. 2016. Mutation in ADORA1 identified as likely cause of early-onset parkinsonism and cognitive dysfunction. In Movement disorders : official journal of the Movement Disorder Society, 31, 1004-11. doi:10.1002/mds.26627. https://pubmed.ncbi.nlm.nih.gov/27134041/

4. Wong, Poh Kuan, Syafruddin, Saiful Effendi, Cheah, Fook Choe, Ng, Pei Yuen, Chua, Eng Wee. 2024. Introduction of a single-nucleotide variant, rs16851030, into the ADORA1 gene increased cellular susceptibility to hypoxia. In Personalized medicine, 21, 353-366. doi:10.1080/17410541.2024.2412514. https://pubmed.ncbi.nlm.nih.gov/39440484/

5. Pang, Li, Ng, Kevin Tak-Pan, Liu, Jiang, Lo, Chung-Mau, Man, Kwan. 2021. Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma. In Cancer letters, 522, 80-92. doi:10.1016/j.canlet.2021.09.022. https://pubmed.ncbi.nlm.nih.gov/34536555/