Impa2-flox 基因敲除小鼠

1. Wang, Liuli, Liu, Deming, Liu, Shuo, Ma, Haizhong, Cai, Hui. 2022. Identification of IMPA2 as the hub gene associated with colorectal cancer and liver metastasis by integrated bioinformatics analysis. In Translational oncology, 21, 101435. doi:10.1016/j.tranon.2022.101435. https://pubmed.ncbi.nlm.nih.gov/35483170/

2. Xie, Kexin, Liu, Lei, Wang, Min, Lin, Yingrui, Zhu, Xiaolin. . IMPA2 blocks cervical cancer cell apoptosis and induces paclitaxel resistance through p53-mediated AIFM2 regulation. In Acta biochimica et biophysica Sinica, 55, 623-632. doi:10.3724/abbs.2023069. https://pubmed.ncbi.nlm.nih.gov/37140233/

3. Zhang, Kan, Liu, Lei, Wang, Min, Tan, Shan, Luo, Lingli. 2020. A novel function of IMPA2, plays a tumor-promoting role in cervical cancer. In Cell death & disease, 11, 371. doi:10.1038/s41419-020-2507-z. https://pubmed.ncbi.nlm.nih.gov/32409648/

4. Lei, Xingyu, Liao, Ruocen, Chen, Xingyu, Dai, Zhijun, Dong, Chenfang. 2023. IMPA2 promotes basal-like breast cancer aggressiveness by a MYC-mediated positive feedback loop. In Cancer letters, 582, 216527. doi:10.1016/j.canlet.2023.216527. https://pubmed.ncbi.nlm.nih.gov/38048842/