Fbxw11-flox 基因敲除小鼠

1. Tan, Peng, Cai, Shuang, Huang, Zhiwei, Fu, Wenguang, Zhao, Lingyu. 2024. E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic cancer. In Cellular signalling, 116, 111033. doi:10.1016/j.cellsig.2024.111033. https://pubmed.ncbi.nlm.nih.gov/38182068/

2. Yao, Jing, Yang, Jun, Yang, Zhe, Ji, Bing, Zhang, Zheng-Yun. 2021. FBXW11 contributes to stem-cell-like features and liver metastasis through regulating HIC1-mediated SIRT1 transcription in colorectal cancer. In Cell death & disease, 12, 930. doi:10.1038/s41419-021-04185-7. https://pubmed.ncbi.nlm.nih.gov/34642302/

3. Sun, Jingjie, Qin, Xiaodong, Zhang, Xinyan, Zhang, Wei, Wang, Manxia. 2021. FBXW11 deletion alleviates Alzheimer's disease by reducing neuroinflammation and amyloid-β plaque formation via repression of ASK1 signaling. In Biochemical and biophysical research communications, 548, 104-111. doi:10.1016/j.bbrc.2020.12.081. https://pubmed.ncbi.nlm.nih.gov/33640602/

4. Wang, Lina, Feng, Wenli, Yang, Xiao, Zhu, Xiaofan, Zheng, Guoguang. 2018. Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways. In Cell death & disease, 9, 427. doi:10.1038/s41419-018-0440-1. https://pubmed.ncbi.nlm.nih.gov/29555946/