Slc15a4-flox 基因敲除小鼠

1. Heinz, Leonhard X, Lee, JangEun, Kapoor, Utkarsh, Rebsamen, Manuele, Superti-Furga, Giulio. 2020. TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. In Nature, 581, 316-322. doi:10.1038/s41586-020-2282-0. https://pubmed.ncbi.nlm.nih.gov/32433612/

2. Mazzei, Aurora, Serino, Grazia, Romano, Alessandro, Verri, Tiziano, Barca, Amilcare. 2022. Identification of SLC15A4/PHT1 Gene Products Upregulation Marking the Intestinal Epithelial Monolayer of Ulcerative Colitis Patients. In International journal of molecular sciences, 23, . doi:10.3390/ijms232113170. https://pubmed.ncbi.nlm.nih.gov/36361959/

3. Kobayashi, Toshihiko, Nguyen-Tien, Dat, Sorimachi, Yuriko, Suematsu, Makoto, Toyama-Sorimachi, Noriko. . SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress. In Proceedings of the National Academy of Sciences of the United States of America, 118, . doi:10.1073/pnas.2100295118. https://pubmed.ncbi.nlm.nih.gov/34385317/

4. Rimann, Ivo, Gonzalez-Quintial, Rosana, Baccala, Roberto, Kono, Dwight H, Theofilopoulos, Argyrios N. 2022. The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes. In Proceedings of the National Academy of Sciences of the United States of America, 119, e2200544119. doi:10.1073/pnas.2200544119. https://pubmed.ncbi.nlm.nih.gov/35349343/

5. Skopelitou, Diamanto, Srivastava, Aayushi, Miao, Beiping, Försti, Asta, Reddy Bandapalli, Obul. 2022. Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer. In Molecular genetics and genomics : MGG, 297, 965-979. doi:10.1007/s00438-022-01896-0. https://pubmed.ncbi.nlm.nih.gov/35562597/