Acy1-KO 基因敲除小鼠

1. Shan, Wulin, Dai, Chunyang, Zhang, Huanhuan, Yi, Qiyi, Xia, Bairong. 2022. ACY1 Downregulation Enhances the Radiosensitivity of Cetuximab-Resistant Colorectal Cancer by Inactivating the Wnt/β-Catenin Signaling Pathway. In Cancers, 14, . doi:10.3390/cancers14225704. https://pubmed.ncbi.nlm.nih.gov/36428796/

2. Chen, Hong, Wang, Wei, Xiao, Caizhi, Li, Fangfei, Liu, Shaoyong. . ACY1 regulating PTEN/PI3K/AKT signaling in the promotion of non-small cell lung cancer progression. In Annals of translational medicine, 9, 1378. doi:10.21037/atm-21-3127. https://pubmed.ncbi.nlm.nih.gov/34733930/

3. Mauri, Alessia, Saielli, Laura Assunta, Alfei, Enrico, Spaccini, Luigina, Cereda, Cristina. 2023. Menkes disease complicated by concurrent ACY1 deficiency: A case report. In Frontiers in genetics, 14, 1077625. doi:10.3389/fgene.2023.1077625. https://pubmed.ncbi.nlm.nih.gov/36936426/

4. Lin, Xiao-Tong, Luo, Yuan-Deng, Mao, Cui, Tan, De-Hong, Xie, Chuan-Ming. 2024. Integrated ubiquitomics characterization of hepatocellular carcinomas. In Hepatology (Baltimore, Md.), , . doi:10.1097/HEP.0000000000001096. https://pubmed.ncbi.nlm.nih.gov/39348425/

5. Liu, Baowen, Wu, Wenyao, Cui, LingLing, Zhang, Xianwei, Duan, Guangyou. 2023. A novel co-target of ACY1 governing plasma membrane translocation of SphK1 contributes to inflammatory and neuropathic pain. In iScience, 26, 106989. doi:10.1016/j.isci.2023.106989. https://pubmed.ncbi.nlm.nih.gov/37378314/

6. Yu, Bing, Liu, Xuezhong, Cao, Xiuzhen, Zhang, Mingyue, Chang, Hong. 2017. Study of the expression and function of ACY1 in patients with colorectal cancer. In Oncology letters, 13, 2459-2464. doi:10.3892/ol.2017.5702. https://pubmed.ncbi.nlm.nih.gov/28454420/

7. Bomba, Lorenzo, Walter, Klaudia, Guo, Qi, Butterworth, Adam S, Soranzo, Nicole. 2022. Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites. In American journal of human genetics, 109, 1038-1054. doi:10.1016/j.ajhg.2022.04.009. https://pubmed.ncbi.nlm.nih.gov/35568032/

8. Ferri, L, Funghini, S, Fioravanti, A, Donati, M A, Morrone, A. 2013. Aminoacylase I deficiency due to ACY1 mRNA exon skipping. In Clinical genetics, 86, 367-72. doi:10.1111/cge.12297. https://pubmed.ncbi.nlm.nih.gov/24117009/

9. Wang, Guanbo, Li, Hai, Hou, Yi. 2021. LncRNA MAGI2-AS3 inhibits tumor progression and angiogenesis by regulating ACY1 via interacting with transcription factor HEY1 in clear cell renal cell carcinoma. In Cancer gene therapy, 29, 585-596. doi:10.1038/s41417-021-00339-z. https://pubmed.ncbi.nlm.nih.gov/34002044/