Slc6a2-flox 基因敲除小鼠

1. Xia, Zhuoman, Cao, Zhihong, Surento, Wesley, Lu, Guangming, Qi, Rongfeng. 2024. Relationship between SLC6A2 gene polymorphisms and brain volume in Han Chinese adults who lost their sole child. In BMC psychiatry, 24, 11. doi:10.1186/s12888-023-05467-4. https://pubmed.ncbi.nlm.nih.gov/38166870/

2. Kim, Sun-Young, Kim, Han-Na, Jeon, Sang Won, Kim, Se Young, Kim, Yong-Ku. 2020. Association between genetic variants of the norepinephrine transporter gene (SLC6A2) and bipolar I disorder. In Progress in neuro-psychopharmacology & biological psychiatry, 107, 110227. doi:10.1016/j.pnpbp.2020.110227. https://pubmed.ncbi.nlm.nih.gov/33340618/

3. Pirzgalska, Roksana M, Seixas, Elsa, Seidman, Jason S, Glass, Christopher K, Domingos, Ana I. 2017. Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine. In Nature medicine, 23, 1309-1318. doi:10.1038/nm.4422. https://pubmed.ncbi.nlm.nih.gov/29035364/

4. Guilherme, João Paulo L F, Bigliassi, Marcelo, Lancha Junior, Antonio H. 2019. Association study of SLC6A2 gene Thr99Ile variant (rs1805065) with athletic status in the Brazilian population. In Gene, 707, 53-57. doi:10.1016/j.gene.2019.05.013. https://pubmed.ncbi.nlm.nih.gov/31075414/

5. Shang, Chi-Yung, Chiang, Huey-Ling, Gau, Susan Shur-Fen. 2014. A haplotype of the norepinephrine transporter gene (SLC6A2) is associated with visual memory in attention-deficit/hyperactivity disorder. In Progress in neuro-psychopharmacology & biological psychiatry, 58, 89-96. doi:10.1016/j.pnpbp.2014.12.010. https://pubmed.ncbi.nlm.nih.gov/25554436/

6. Kim, Yong-Ku, Hwang, Jung-A, Lee, Heon-Jeong, Hahn, Sang-Woo, Na, Kyoung-Sae. 2014. Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder. In Journal of affective disorders, 158, 127-32. doi:10.1016/j.jad.2014.01.018. https://pubmed.ncbi.nlm.nih.gov/24655776/

7. Harikrishnan, K N, Bayles, Richard, Ciccotosto, Giuseppe D, Christodoulou, John, El-Osta, Assam. . Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons. In The Journal of neuroscience : the official journal of the Society for Neuroscience, 30, 1494-501. doi:10.1523/JNEUROSCI.4675-09.2010. https://pubmed.ncbi.nlm.nih.gov/20107077/

8. Verschure, Derk O, Baas, F, van Eck-Smit, Berthe L F, Somsen, G Aernout, Verberne, Hein J. 2016. Polymorphism of SLC6A2 gene does not influence outcome of myocardial 123I-mIBG scintigraphy in patients with chronic heart failure. In Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 25, 900-906. doi:10.1007/s12350-016-0722-x. https://pubmed.ncbi.nlm.nih.gov/27844334/

9. Wang, Minmin, Li, Meng, Zhao, Haizhao, Zhao, Cuifen, Li, Baomin. 2025. Roles of Single Nucleotide Polymorphisms in the SLC6A2 Gene in the Risk of Vasovagal Syncope Among Children in Eastern China: A Case-Control Study. In Health science reports, 8, e70585. doi:10.1002/hsr2.70585. https://pubmed.ncbi.nlm.nih.gov/40114755/