Akt1-KO 基因敲除小鼠

1. Kong, Kyoung-Ah, Lee, Ji-Yeon, Oh, Ji Hoon, Lee, Youra, Kim, Myoung Hee. 2014. Akt1 mediates the posterior Hoxc gene expression through epigenetic modifications in mouse embryonic fibroblasts. In Biochimica et biophysica acta, 1839, 793-9. doi:10.1016/j.bbagrm.2014.06.011. https://pubmed.ncbi.nlm.nih.gov/24955524/

2. Zhao, Jingjing, Zeng, Xue, Song, Ping, Wu, Xiaohong, Shi, Hongbo. 2016. AKT1 as the PageRank hub gene is associated with melanoma and its functional annotation is highly related to the estrogen signaling pathway that may regulate the growth of melanoma. In Oncology reports, 36, 2087-93. doi:10.3892/or.2016.5048. https://pubmed.ncbi.nlm.nih.gov/27573172/

3. George, Bijesh, Gui, Bin, Raguraman, Rajeswari, Pillai, Madhavan Radhakrishna, Kumar, Rakesh. 2022. AKT1 Transcriptomic Landscape in Breast Cancer Cells. In Cells, 11, . doi:10.3390/cells11152290. https://pubmed.ncbi.nlm.nih.gov/35892586/

4. Zhang, Lanlan, Yan, Ting, Wang, Wenmeng, Li, Yuhua, Sui, Guangchao. 2021. AKT1 is positively regulated by G-quadruplexes in its promoter and 3'-UTR. In Biochemical and biophysical research communications, 561, 93-100. doi:10.1016/j.bbrc.2021.05.029. https://pubmed.ncbi.nlm.nih.gov/34020144/

5. Palma, Martine, Leroy, Catherine, Salomé-Desnoulez, Sophie, Le Hir, Hervé, Lejeune, Fabrice. . A role for AKT1 in nonsense-mediated mRNA decay. In Nucleic acids research, 49, 11022-11037. doi:10.1093/nar/gkab882. https://pubmed.ncbi.nlm.nih.gov/34634811/