Abcc3位于小鼠的11号染色体,采用CRISPR/Cas技术,设计sgRNA和ssDNA,通过高通量电转受精卵方式,获得Abcc3基因条件性敲除小鼠,性成熟后取精子冻存。
相关疾病:
Colorectal Cancer
Cholestasis
Lung Cancer
Hepatocellular Carcinoma
Dubin-Johnson Syndrome
Pancreatic Cancer
Ovarian Cancer
Colon Adenocarcinoma
Bladder Cancer
Extrahepatic Cholestasis