智鼠故事 
C57BL/6JCya-Cd226em1flox/Cya 条件性基因敲除小鼠
复苏/繁育服务
产品名称
Cd226-flox
产品编号
S-CKO-17615
品系全称
C57BL/6JCya-Cd226em1flox/Cya
品系背景
C57BL/6JCya
品系编号
CKOCMP-225825-Cd226-B6J-VB
品系状态
使用本品系发表的文献需注明： Cd226-flox mice (Strain S-CKO-17615) were purchased from Cyagen.
交付类型
周龄
性别
基因型
数量
基因
基因别称
Pta1，DNAM1，DNAM-1，TLiSA1
NCBI ID
染色体号
Chr 18
NCBI RefSeq
NM_178687
Ensembl ID
ENSMUST00000037142
修饰方式
条件性基因敲除
靶向范围
Exon 2~3
敲除长度
~1.3 kb
品系说明
该品系是基于策略设计时的数据库信息制作而成，建议您在购买前查询最新的数据库和相关文献，以获取最准确的表型信息。
表型提示
MGI:3039602Mice homozygous for a knock-out allele exhibit impaired NK cell cytolysis and increased incidence of tumor formation and mortality.
发表文献
Cell Death & Disease
2024-09-01
CD226 implicated in Akt-dependent apoptosis of CD4+ T cell contributes to asthmatic pathogenesis
Immunology
2023-03-20
CD226 deficiency exacerbated intestinal immune dysregulation in mice with dinitrochlorobenzene-induced atopic dermatitis
Mediators of Inflflammation
2022-05-25
CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses
JOURNAL OF LEUKOCYTE BIOLOGY
2019-12-19
CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340.
1
发表文献
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