Thumpd2-flox 基因敲除小鼠

1. Wang, Can, Ulryck, Nathalie, Herzel, Lydia, Bohnsack, Katherine E, Graille, Marc. . N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing. In Nucleic acids research, 51, 7496-7519. doi:10.1093/nar/gkad487. https://pubmed.ncbi.nlm.nih.gov/37283053/

2. Hua, Minhui, Chen, Yujie, Jia, Meiqun, Xu, Yunzhao, Zhang, Yuquan. 2024. RNA-binding protein THUMPD2 inhibits proliferation and promotes metastasis in epithelial ovarian cancer. In Heliyon, 10, e33201. doi:10.1016/j.heliyon.2024.e33201. https://pubmed.ncbi.nlm.nih.gov/39071668/

3. Hayashi, Masato, Kawakubo, Hirofumi, Fukuda, Kazumasa, Wada, Norihito, Kitagawa, Yuko. 2019. THUMP domain containing 2 protein possibly induces resistance to cisplatin and 5-fluorouracil in in vitro human esophageal squamous cell carcinoma cells as revealed by transposon activation mutagenesis. In The journal of gene medicine, 21, e3135. doi:10.1002/jgm.3135. https://pubmed.ncbi.nlm.nih.gov/31656051/