Six1-flox 基因敲除小鼠

1. Hughes, Connor J, Fields, Kaiah M, Danis, Etienne P, Jedlicka, Paul, Ford, Heide L. 2023. SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma. In Nature communications, 14, 4357. doi:10.1038/s41467-023-39945-w. https://pubmed.ncbi.nlm.nih.gov/37468459/

2. Guo, Liantao, Li, Faminzi, Liu, Hanqing, Chen, Chuang, Sun, Shengrong. 2023. SIX1 amplification modulates stemness and tumorigenesis in breast cancer. In Journal of translational medicine, 21, 866. doi:10.1186/s12967-023-04679-2. https://pubmed.ncbi.nlm.nih.gov/38031089/

3. Li, Ling, Liang, Yingchun, Kang, Lei, Xu, Xiaojie, Ye, Qinong. 2018. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. In Cancer cell, 33, 368-385.e7. doi:10.1016/j.ccell.2018.01.010. https://pubmed.ncbi.nlm.nih.gov/29455928/

4. Negrisolo, Susanna, Centi, Sonia, Benetti, Elisa, Murer, Luisa, Artifoni, Lina. 2014. SIX1 gene: absence of mutations in children with isolated congenital anomalies of kidney and urinary tract. In Journal of nephrology, 27, 667-71. doi:10.1007/s40620-014-0112-x. https://pubmed.ncbi.nlm.nih.gov/24899122/

5. Nagel, Stefan, Meyer, Corinna, Kaufmann, Maren, Drexler, Hans G, MacLeod, Roderick A F. . Aberrant expression of homeobox gene SIX1 in Hodgkin lymphoma. In Oncotarget, 6, 40112-26. doi:10.18632/oncotarget.5556. https://pubmed.ncbi.nlm.nih.gov/26473286/

6. Wang, Junzheng, Liu, Manling, Zhao, Lihua, Dai, Yifan, Li, Rongfeng. 2019. Disabling of nephrogenesis in porcine embryos via CRISPR/Cas9-mediated SIX1 and SIX4 gene targeting. In Xenotransplantation, 26, e12484. doi:10.1111/xen.12484. https://pubmed.ncbi.nlm.nih.gov/30623494/