Memo1 深入了解基因-突变-疾病-模型全维度数据，尽在Rare Disease Data Center（RDDC）综合数据库

MGI:1924140 Mice homozygous for null alleles display strain background dependent lethality and defects in vasculogenesis or endochondral bone development. Mice homozygous for a floxed allele activated postnatally exhibit a reduced life span, increased insulin sensitivity, small stature, graying hair, alopecia, kyphosis, loss of subcutaneous fat, loss of spermatozoa in the epididymis and increased active vitamin D.