Amn 深入了解基因-突变-疾病-模型全维度数据，尽在Rare Disease Data Center（RDDC）综合数据库

MGI:1934943 Homozygous mutation of this gene results in embryonic growth arrest between the mid and late streak stages of gastrulation and abnormal ectoderm formation, followed by death. Generation of middle primitive streak derivatives is impaired, leading to absence of mesoderm and somites.