Adcy6-KO 基因敲除小鼠

1. Li, Weijing, Sang, Meixiang, Hao, Xiaoguang, Wang, Yong, Shan, Baoen. 2019. Gene expression and DNA methylation analyses suggest that immune process-related ADCY6 is a prognostic factor of luminal-like breast cancer. In Journal of cellular biochemistry, 121, 3537-3546. doi:10.1002/jcb.29633. https://pubmed.ncbi.nlm.nih.gov/31886586/

2. Jia, Linna, Jiang, Yunfeng, Li, Xinzhi, Chen, Zheng. 2019. Purβ promotes hepatic glucose production by increasing Adcy6 transcription. In Molecular metabolism, 31, 85-97. doi:10.1016/j.molmet.2019.11.008. https://pubmed.ncbi.nlm.nih.gov/31918924/

3. Wang, Wenyan, Xue, Yingying, Li, Dujuan, Sun, Ning, Chen, Qi. 2024. Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway. In European journal of pharmacology, 978, 176770. doi:10.1016/j.ejphar.2024.176770. https://pubmed.ncbi.nlm.nih.gov/38925286/

4. Laquérriere, Annie, Maluenda, Jérome, Camus, Adrien, Tawk, Marcel, Melki, Judith. 2013. Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects. In Human molecular genetics, 23, 2279-89. doi:10.1093/hmg/ddt618. https://pubmed.ncbi.nlm.nih.gov/24319099/