Folr2-KO 基因敲除小鼠

1. Sharma, Ankur, Seow, Justine Jia Wen, Dutertre, Charles-Antoine, Ginhoux, Florent, DasGupta, Ramanuj. 2020. Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma. In Cell, 183, 377-394.e21. doi:10.1016/j.cell.2020.08.040. https://pubmed.ncbi.nlm.nih.gov/32976798/

2. Song, Xinli, Wei, Jianhui, Shu, Jing, Zhu, Ping, Qin, Jiabi. 2022. Association of polymorphisms of FOLR1 gene and FOLR2 gene and maternal folic acid supplementation with risk of ventricular septal defect: a case-control study. In European journal of clinical nutrition, 76, 1273-1280. doi:10.1038/s41430-022-01110-9. https://pubmed.ncbi.nlm.nih.gov/35273364/

3. Dick, Sarah A, Wong, Anthony, Hamidzada, Homaira, Mak, Tak W, Epelman, Slava. 2022. Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles. In Science immunology, 7, eabf7777. doi:10.1126/sciimmunol.abf7777. https://pubmed.ncbi.nlm.nih.gov/34995099/

4. Xu, Xiaohua, Jiang, Jianyang, Yao, Lijuan, Ji, Bing. 2018. Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling. In Medical science monitor : international medical journal of experimental and clinical research, 24, 8064-8073. doi:10.12659/MSM.911384. https://pubmed.ncbi.nlm.nih.gov/30415267/

5. Moore, Peter K, Anderson, Kelsey C, McManus, Shannon A, Janssen, William J, McCubbrey, Alexandra L. 2023. Single-cell RNA sequencing reveals unique monocyte-derived interstitial macrophage subsets during lipopolysaccharide-induced acute lung inflammation. In American journal of physiology. Lung cellular and molecular physiology, 324, L536-L549. doi:10.1152/ajplung.00223.2022. https://pubmed.ncbi.nlm.nih.gov/36852927/

6. Song, Xinli, Huang, Peng, Wang, Tingting, Chen, Letao, Qin, Jiabi. . Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study. In Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 47, 52-62. doi:10.11817/j.issn.1672-7347.2022.200992. https://pubmed.ncbi.nlm.nih.gov/35545363/

7. Bugatti, Mattia, Bergamini, Marco, Missale, Francesco, Benvenuti, Federica, Vermi, William. . A Population of TIM4+FOLR2+ Macrophages Localized in Tertiary Lymphoid Structures Correlates to an Active Immune Infiltrate Across Several Cancer Types. In Cancer immunology research, 10, 1340-1353. doi:10.1158/2326-6066.CIR-22-0271. https://pubmed.ncbi.nlm.nih.gov/36122412/

8. Liu, Xiaoyu, Xu, Xu, Wu, Zhuozhuo, Huang, Wei, Wang, Zhongmin. 2022. Integrated single-cell RNA-seq analysis identifies immune heterogeneity associated with KRAS/TP53 mutation status and tumor-sideness in colorectal cancers. In Frontiers in immunology, 13, 961350. doi:10.3389/fimmu.2022.961350. https://pubmed.ncbi.nlm.nih.gov/36172359/

9. Xiang, Chan, Zhang, Min, Shang, Zhanxian, Yu, Yang, Han, Yuchen. 2023. Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma. In Cell death & disease, 14, 493. doi:10.1038/s41419-023-06021-6. https://pubmed.ncbi.nlm.nih.gov/37532692/