Srrm3-KO 基因敲除小鼠

1. Juan-Mateu, Jonàs, Bajew, Simon, Miret-Cuesta, Marta, Valcárcel, Juan, Irimia, Manuel. 2023. Pancreatic microexons regulate islet function and glucose homeostasis. In Nature metabolism, 5, 219-236. doi:10.1038/s42255-022-00734-2. https://pubmed.ncbi.nlm.nih.gov/36759540/

2. Ciampi, Ludovica, Mantica, Federica, López-Blanch, Laura, Head, Sarah A, Irimia, Manuel. 2022. Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision. In Proceedings of the National Academy of Sciences of the United States of America, 119, e2117090119. doi:10.1073/pnas.2117090119. https://pubmed.ncbi.nlm.nih.gov/35858306/

3. Nakano, Yoko, Wiechert, Susan, Fritzsch, Bernd, Bánfi, Botond. 2020. Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. In Life science alliance, 3, . doi:10.26508/lsa.202000841. https://pubmed.ncbi.nlm.nih.gov/33087486/

4. Lee, Nan Sook, Evgrafov, Oleg V, Souaiaia, Tade, Shung, K Kirk, Chow, Robert H. 2015. Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness. In Scientific reports, 5, 11207. doi:10.1038/srep11207. https://pubmed.ncbi.nlm.nih.gov/26053433/