Sil1-KO 基因敲除小鼠

1. Inaguma, Yutaka, Hamada, Nanako, Tabata, Hidenori, Kumagai, Toshiyuki, Nagata, Koh-ichi. 2014. SIL1, a causative cochaperone gene of Marinesco-Söjgren syndrome, plays an essential role in establishing the architecture of the developing cerebral cortex. In EMBO molecular medicine, 6, 414-29. doi:10.1002/emmm.201303069. https://pubmed.ncbi.nlm.nih.gov/24473200/

2. Xu, Shilian, Zhu, Jia, Mi, Kai, Shen, Yan, Zhang, Xiaomin. 2019. Functional Role of SIL1 in Neurodevelopment and Learning. In Neural plasticity, 2019, 9653024. doi:10.1155/2019/9653024. https://pubmed.ncbi.nlm.nih.gov/31531014/

3. Wang, Qunxian, Jiang, Yanshuang, Meng, Zijun, Zhou, Weihui, Song, Weihong. . SIL1 improves cognitive impairment in APP23/PS45 mice by regulating amyloid precursor protein processing and Aβ generation. In Zoological research, 45, 845-856. doi:10.24272/j.issn.2095-8137.2023.363. https://pubmed.ncbi.nlm.nih.gov/39004862/

4. Xu, Hao, Xu, Shangchen, Zhang, Rui, Xin, Tao, Pang, Qi. 2018. SIL1 functions as an oncogene in glioma by AKT/mTOR signaling pathway. In OncoTargets and therapy, 11, 3775-3783. doi:10.2147/OTT.S167552. https://pubmed.ncbi.nlm.nih.gov/29997438/