Mlkl-KO 基因敲除小鼠

1. Zhan, Chaoning, Huang, Minchun, Yang, Xiaojun, Hou, Jin. 2021. MLKL: Functions beyond serving as the Executioner of Necroptosis. In Theranostics, 11, 4759-4769. doi:10.7150/thno.54072. https://pubmed.ncbi.nlm.nih.gov/33754026/

2. Lawlor, Kate E, Murphy, James M, Vince, James E. . Gasdermin and MLKL necrotic cell death effectors: Signaling and diseases. In Immunity, 57, 429-445. doi:10.1016/j.immuni.2024.02.011. https://pubmed.ncbi.nlm.nih.gov/38479360/

3. Geng, Lu, Gao, Wenqing, Saiyin, Hexige, Zhang, Zhuohua, Li, Jixi. 2023. MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease. In Molecular neurodegeneration, 18, 94. doi:10.1186/s13024-023-00686-5. https://pubmed.ncbi.nlm.nih.gov/38041169/

4. Majdi, Amine, Aoudjehane, Lynda, Ratziu, Vlad, Housset, Chantal, Gautheron, Jérémie. 2019. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease. In Journal of hepatology, 72, 627-635. doi:10.1016/j.jhep.2019.11.008. https://pubmed.ncbi.nlm.nih.gov/31760070/

5. Zhang, Kaiying, Chen, Xiaoxin, Zhou, Rong, Qiu, Wei, Fang, Fuchun. 2023. Inhibition of gingival fibroblast necroptosis mediated by RIPK3/MLKL attenuates periodontitis. In Journal of clinical periodontology, 50, 1264-1279. doi:10.1111/jcpe.13841. https://pubmed.ncbi.nlm.nih.gov/37366309/