Ulk3-KO 基因敲除小鼠

1. Goruppi, Sandro, Clocchiatti, Andrea, Bottoni, Giulia, Simon, Christian, Paolo Dotto, G. 2023. The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome. In Nature communications, 14, 887. doi:10.1038/s41467-023-36410-6. https://pubmed.ncbi.nlm.nih.gov/36797248/

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3. Jin, Yuxi, Zhao, Lin, Zhang, Yanli, Xiao, Ming, Sheng, Chengyu. 2024. BIN1 deficiency enhances ULK3-dependent autophagic flux and reduces dendritic size in mouse hippocampal neurons. In Autophagy, 21, 223-242. doi:10.1080/15548627.2024.2393932. https://pubmed.ncbi.nlm.nih.gov/39171951/

4. Lee, Hyeon-Ju, Kang, Ji-One, Kim, Sung-Moon, Lee, Young-Ho, Oh, Bermseok. 2016. Gene Silencing and Haploinsufficiency of Csk Increase Blood Pressure. In PloS one, 11, e0146841. doi:10.1371/journal.pone.0146841. https://pubmed.ncbi.nlm.nih.gov/26751575/

5. Hodonsky, Chani J, Turner, Adam W, Khan, Mohammad Daud, Björkegren, Johan L M, Miller, Clint L. 2023. Multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci. In Cell genomics, 4, 100465. doi:10.1016/j.xgen.2023.100465. https://pubmed.ncbi.nlm.nih.gov/38190101/

6. Jing, Yipei, Jiang, Xueke, Lei, Li, Yang, Zesong, Zhang, Ling. 2021. Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3. In Journal of experimental & clinical cancer research : CR, 40, 312. doi:10.1186/s13046-021-02122-2. https://pubmed.ncbi.nlm.nih.gov/34615546/

7. González-Rodríguez, Patricia, Cheray, Mathilde, Keane, Lily, Engskog-Vlachos, Pinelopi, Joseph, Bertrand. 2022. ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction. In Autophagy, 18, 2769-2780. doi:10.1080/15548627.2022.2039993. https://pubmed.ncbi.nlm.nih.gov/35226587/

8. Kasak, Lagle, Näks, Mihkel, Eek, Priit, Kasvandik, Sergo, Piirsoo, Marko. 2018. Characterization of Protein Kinase ULK3 Regulation by Phosphorylation and Inhibition by Small Molecule SU6668. In Biochemistry, 57, 5456-5465. doi:10.1021/acs.biochem.8b00356. https://pubmed.ncbi.nlm.nih.gov/30096229/

9. Goruppi, Sandro, Procopio, Maria-Giuseppina, Jo, Seunghee, Neel, Victor, Dotto, G Paolo. . The ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI. In Cell reports, 20, 2468-2479. doi:10.1016/j.celrep.2017.08.048. https://pubmed.ncbi.nlm.nih.gov/28877478/

10. Maloverjan, Alla, Piirsoo, Marko, Kasak, Lagle, Østerlund, Torben, Kogerman, Priit. 2010. Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathway. In The Journal of biological chemistry, 285, 30079-90. doi:10.1074/jbc.M110.133991. https://pubmed.ncbi.nlm.nih.gov/20643644/