Micu2-KO 基因敲除小鼠

1. Vishnu, N, Hamilton, A, Bagge, A, Nicholls, D G, Mulder, H. 2021. Mitochondrial clearance of calcium facilitated by MICU2 controls insulin secretion. In Molecular metabolism, 51, 101239. doi:10.1016/j.molmet.2021.101239. https://pubmed.ncbi.nlm.nih.gov/33932586/

2. Robert, Alison, Crottès, David, Bourgeais, Jérôme, Raoul, William, Guéguinou, Maxime. 2024. MICU2 up-regulation enhances tumor aggressiveness and metabolic reprogramming during colorectal cancer development. In PLoS biology, 22, e3002854. doi:10.1371/journal.pbio.3002854. https://pubmed.ncbi.nlm.nih.gov/39466877/

3. Bick, Alexander G, Wakimoto, Hiroko, Kamer, Kimberli J, Seidman, J G, Seidman, Christine E. 2017. Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. In Proceedings of the National Academy of Sciences of the United States of America, 114, E9096-E9104. doi:10.1073/pnas.1711303114. https://pubmed.ncbi.nlm.nih.gov/29073106/

4. Plovanich, Molly, Bogorad, Roman L, Sancak, Yasemin, Koteliansky, Victor, Mootha, Vamsi K. 2013. MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling. In PloS one, 8, e55785. doi:10.1371/journal.pone.0055785. https://pubmed.ncbi.nlm.nih.gov/23409044/