Defb23-KO 基因敲除小鼠

[1] 张国亮, 孙元超, 关明凯, 刘梦梦, 孙世铎. 单细胞和空间转录组学研究揭示小鼠精子成熟过程中β-防御素基因家族的时空特异性. 细胞通讯与信号 : CCS, 2024, 22, 267.

[2] 张超宝, 周宇川, 谢胜松, 尹勤, 唐成, 尼智, 费建, 张永连. CRISPR/Cas9介导的基因组编辑揭示了大鼠附睾中β-防御素家族成员对精子成熟的协同作用. FASEB期刊 : 官方出版物, 2018, 32, 1354-1363.

参考文献：

1. Zhang, Guoliang, Sun, Yuanchao, Guan, Minkai, Liu, Mengmeng, Sun, Shiduo. 2024. Single-cell and spatial transcriptomic investigation reveals the spatiotemporal specificity of the beta-defensin gene family during mouse sperm maturation. In Cell communication and signaling : CCS, 22, 267. doi:10.1186/s12964-024-01637-3. https://pubmed.ncbi.nlm.nih.gov/38745232/

2. Zhang, Chaobao, Zhou, Yuchuan, Xie, Shengsong, Fei, Jian, Zhang, Yonglian. 2018. CRISPR/Cas9-mediated genome editing reveals the synergistic effects of β-defensin family members on sperm maturation in rat epididymis. In FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32, 1354-1363. doi:10.1096/fj.201700936R. https://pubmed.ncbi.nlm.nih.gov/29141997/