Usp11-KO 基因敲除小鼠

1. Chen, Jin, Ning, Deng, Du, Pengcheng, Zhang, Bixiang, Chen, Xiaoping. 2023. USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma. In Oncogene, 43, 123-135. doi:10.1038/s41388-023-02847-8. https://pubmed.ncbi.nlm.nih.gov/37973952/

2. Sun, Hongze, Ou, Baochi, Zhao, Senlin, Wang, Rangrang, Peng, Zhihai. 2019. USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway. In EBioMedicine, 48, 236-247. doi:10.1016/j.ebiom.2019.08.061. https://pubmed.ncbi.nlm.nih.gov/31521612/

3. Shi, Yingfeng, Tao, Min, Chen, Hui, Zhuang, Shougang, Liu, Na. 2022. Ubiquitin-specific protease 11 promotes partial epithelial-to-mesenchymal transition by deubiquitinating the epidermal growth factor receptor during kidney fibrosis. In Kidney international, 103, 544-564. doi:10.1016/j.kint.2022.11.027. https://pubmed.ncbi.nlm.nih.gov/36581018/

4. Jurga, Mateusz, Abugable, Arwa A, Goldman, Alastair S H, El-Khamisy, Sherif F. 2021. USP11 controls R-loops by regulating senataxin proteostasis. In Nature communications, 12, 5156. doi:10.1038/s41467-021-25459-w. https://pubmed.ncbi.nlm.nih.gov/34526504/