Ndrg4-KO 基因敲除小鼠

1. Cao, Longlong, Hu, Tianling, Lu, Heng, Peng, Dunfa. 2020. N-MYC Downstream Regulated Gene 4 (NDRG4), a Frequent Downregulated Gene through DNA Hypermethylation, plays a Tumor Suppressive Role in Esophageal Adenocarcinoma. In Cancers, 12, . doi:10.3390/cancers12092573. https://pubmed.ncbi.nlm.nih.gov/32927604/

2. Vaes, Nathalie, Schonkeren, Simone L, Rademakers, Glenn, Hofstra, Robert M W, Melotte, Veerle. 2021. Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2. In EMBO reports, 22, e51913. doi:10.15252/embr.202051913. https://pubmed.ncbi.nlm.nih.gov/33890711/

3. Melotte, Veerle, Lentjes, Marjolein H F M, van den Bosch, Sandra M, de Bruïne, Adriaan P, van Engeland, Manon. 2009. N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer. In Journal of the National Cancer Institute, 101, 916-27. doi:10.1093/jnci/djp131. https://pubmed.ncbi.nlm.nih.gov/19535783/

4. Zhao, Changliang, Ren, Yuanyuan, Zhang, Yachao. 2022. NDRG4 Alleviates Myocardial Infarction-Induced Apoptosis through the JAK2/STAT3 Pathway. In Computational and mathematical methods in medicine, 2022, 4869470. doi:10.1155/2022/4869470. https://pubmed.ncbi.nlm.nih.gov/35126626/