Lrrc8d-KO 基因敲除小鼠

1. Widmer, Carmen A, Klebic, Ismar, Domanitskaya, Natalya, Vens, Conchita, Rottenberg, Sven. . Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy. In Cancer research communications, 2, 1266-1281. doi:10.1158/2767-9764.CRC-22-0208. https://pubmed.ncbi.nlm.nih.gov/36467895/

2. Di Meo, Francesco, Iyer, Anjushree, Akama, Keith, Roodman, David G, Perna, Fabiana. . A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma. In Cell reports. Medicine, 4, 101110. doi:10.1016/j.xcrm.2023.101110. https://pubmed.ncbi.nlm.nih.gov/37467717/

3. Stuhlmann, Till, Planells-Cases, Rosa, Jentsch, Thomas J. 2018. LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion. In Nature communications, 9, 1974. doi:10.1038/s41467-018-04353-y. https://pubmed.ncbi.nlm.nih.gov/29773801/

4. König, Benjamin, Stauber, Tobias. 2019. Biophysics and Structure-Function Relationships of LRRC8-Formed Volume-Regulated Anion Channels. In Biophysical journal, 116, 1185-1193. doi:10.1016/j.bpj.2019.02.014. https://pubmed.ncbi.nlm.nih.gov/30871717/